20+ Million Readerbase
Indexed In
  • Academic Journals Database
  • Genamics JournalSeek
  • Academic Keys
  • JournalTOCs
  • China National Knowledge Infrastructure (CNKI)
  • Scimago
  • Access to Global Online Research in Agriculture (AGORA)
  • Electronic Journals Library
  • RefSeek
  • Directory of Research Journal Indexing (DRJI)
  • Hamdard University
  • OCLC- WorldCat
  • SWB online catalog
  • Virtual Library of Biology (vifabio)
  • Publons
  • MIAR
  • University Grants Commission
  • Geneva Foundation for Medical Education and Research
  • Euro Pub
  • Google Scholar
Share This Page
Journal Flyer
Flyer image

Ekpa Emmanuel

Ekpa Emmanuel
Department of Biochemisttry, Ahmadu Bello University, Zaria,

  • Research Article
    Isolation, Partial Purification and Characterization of L-Asparaginase from Hedgehog Serum
    Author(s): Ekpa Emmanuel, Nzelibe HC and Onyike EEkpa Emmanuel, Nzelibe HC and Onyike E

    The need to further explore other sources of therapy for leukemias prompted this current work. It’s already known that L-asparaginase possesses a lot of potentials in the treatment of cancers of the white blood cell but the sources of this enzyme and its properties determine the efficacy of this drug. Generally, for asparaginase to be ideally suited for use in anti-tumor therapy, it had to satisfy a variety of criteria. The organism that is selected should produce the asparaginase in high quantity or yield, and it should be capable of being isolated from simple mammalian sources. The procedures developed for purification of the enzyme should be as rapid and simplified as possible. The purified enzyme should have long term stability on storage, maximal activity at a physiological pH, and a Km for substrate below the concentration of the substrate in the blood. Therefore the aim o.. Read More»
    DOI: 10.4172/1948-5948.1000246

    Abstract PDF