Journal of Microbial & Biochemical Technology

Dereje Damte

Publications

• Research Article
  Evaluation of Anti-Quorum Sensing Activity of 97 Indigenous Plant Extracts From Korea through Bioreporter Bacterial Strains Chromobacterium violaceum and Pseudomonas aeruginosa
  Author(s): Dereje Damte, Elias Gebru, Seung-Jin Lee, Joo-Won Suh and Seung-Chun ParkDereje Damte, Elias Gebru, Seung-Jin Lee, Joo-Won Suh and Seung-Chun Park
  
  Quorum sensing (QS) is a recently discovered chemical communication system that enhances survival of bacteria, as a group allowing resident bacteria to assume specialized roles vital for intra- and inter bacterial gene regulation, and for keeping bacterial colonies intact. Furthermore, with the continuing emergence and spread of multidrug-resistant bacteria, antipathogenic strategy to combat bacterial infections through the interruption of quorum sensing controlled virulence factors had been shown to receive increased attention. With this prospect in the current study, we attempt to screen anti-quorum sensing activity of 97 indigenous plant extracts from Korea, through biomonitor bacterial strains, Chromobacterium violaceum (CV12472) and Pseudomonas aeruginosa (PAO1). Standard disc-diffusion assays were used to detect anti-quorum sensing activity (ring of colorless, but viable cells a.. View More»
  DOI: 10.4172/1948-5948.1000098

  Abstract PDF