Journal of Microbial & Biochemical Technology

Deepika Dave

Publications

• Research Article
  Changes in Cell Structure, Morphology and Activity of Streptomyces venezuelae during the Growth, Shocking and Jadomycin Production Stages
  Author(s): Marianne S Brooks, Tracey J Burdock, Abdel E Ghaly and Deepika DaveMarianne S Brooks, Tracey J Burdock, Abdel E Ghaly and Deepika Dave
  
  Streptomyces venezuelae have the ability to synthesize a group of novel benzoxazolophenanthridine antibiotics called jadomycin. The aim of the study was to investigate the changes in activity, cell structure and morphology of Streptomyces venezuelae while subjected to different environmental conditions during the growth, ethanol shocking, and jadomycin production stages. The activity of S. venezuelae was measured using the triphenyl tetrazolium chloride (TTC) technique while the microbial population was measured using the optical density and plate count techniques. Samples from each stage were viewed under the scanning electron microscope (SEM) and transmission electron microscope (TEM). The specific TF yield was calculated by dividing the TF yield by the number of cells. The specific TF yield remained constant at 2.44 x 10-8(μmol/CFU) during the growth period in nutrient rich medi.. View More»
  DOI: 10.4172/1948-5948.1000073

  Abstract PDF