 
        
						Daniel Oves 
	
					    												
Spain						                            
                            
						
 Research Article
												Isolation, Characterization and Antimicrobial Activities of Actinomycetes
Isolated from a Tunisian Saline Wetland 						
Author(s): Ines Trabelsi, Daniel Oves, Beatriz Gutierrez Magan, Angel Manteca, Olga Genilloud and Mohamed NourInes Trabelsi, Daniel Oves, Beatriz Gutierrez Magan, Angel Manteca, Olga Genilloud and Mohamed Nour             
						
												
				 The “Sebkha of Monastir” is a Tunisian permanent wetland that constitutes a virgin environment to search new biotechnologically relevant microorganisms and activities. A total of 71 different strains were isolated, including 54 Streptomyces, 2 Micromonospora, 2 Nocardia, 4 Pseudonocardia and 9 non-streptomyces actinomyetes. Interesting antimicrobial activities were detected in liquid and solid cultures. The antimicrobial profiles depended upon the culture medium and/or the organic extraction. Several bioactive compounds were identified by liquid chromatography (LC) combined with mass spectrometry (MS) and then analyzed by MEDINA´s database and the Dictionary of Natural Products Chapman & Hall. Isoflavones (genistein and deidzein) are the most produced known active compounds. The chemical structures of four putative novel compounds were elucidated. Interestingly, .. View More»
				  
												DOI:
												 10.4172/1948-5948.1000326