Dae Hyun Lim
	
					    												
Taiwan						                            
                            
						
 Research Article
												Exhaled Nitric Oxide and Symptom Severity in Children with Allergic Rhinitis 						
Author(s): Jeong Hee Kim, Ji Sun Park, Seung Hyun Moon, Dae Hyun Lim, Seon Yeong Hwang and Yoon Sung Park
Jeong Hee Kim, Ji Sun Park, Seung Hyun Moon, Dae Hyun Lim, Seon Yeong Hwang and Yoon Sung Park
             
						
												
				 Objective: There have been few reliable biomarkers to evaluate allergic rhinitis (AR) severity in children. This study aimed to investigate a biomarker for assessing AR severity in children.
Methods: A total of 107 children with AR (80) and non-allergic rhinitis (NAR, 27) were included in this study. The fraction of exhaled nitric oxide (FeNO) was measured and AR severity and duration was graded in patients with AR. We assessed the association between FeNO and the Allergic Rhinitis and its Impact on Asthma (ARIA) classes.
Results: FeNO levels in the AR and NAR groups were 34.7 ± 22.1 and 17.0 ± 13.1 ppb, respectively (p=0.001). FeNO levels were significantly different (p<0.05) in the four ARIA classes: 14.3 ± 3.7 ppb in the mild intermittent group, 22.7 ± 4.8 ppb in the mild persistent grou.. View More»
				  
												DOI:
												 10.4172/2155-6121.1000268