Journal of Microbial & Biochemical Technology

Cathy J Watson

Publications

• Research Article
  Attempt to Detect Garlic Allyl Sulphides from Saliva after Consumption of Garlic Tablets Using GC-MS
  Author(s): Cathy J Watson, David de Souza, Claudio Silva, Dedreia Tull, Suzanne M Garland and Larry L LawsonCathy J Watson, David de Souza, Claudio Silva, Dedreia Tull, Suzanne M Garland and Larry L Lawson
  
  Allicin is an organosulfur compound of Allium sativum (garlic) with anti-fungal and antimicrobial properties. However, to date, neither allicin nor its metabolites has been detected in human organs or bodily fluids following oral consumption of garlic. Bioavailability has only been demonstrated using breath studies. Enteric-coated formulations are designed to pass through the acidic stomach environment; hence detection of garlic compounds in saliva following consumption of enteric-coated garlic tablets would provide evidence of bioavailability in a body secretion. An attempt was made to identify metabolites dially disulphide and allyl methyl sulphide using Gas Chromatography Mass Spectrometry (GC-MS). We completed a single participant mass spectrometry study using 13 time points over 24 hours following consumption of 20 enteric-coated garlic tablets. There was no detection of allicin .. View More»
  DOI: 10.4172/1948-5948.1000104

  Abstract PDF