Journal of Allergy & Therapy

Barbara Collins

Publications

• Research Article
  Hypoallergenicity of a New Extensively Hydrolyzed 100% Whey-based Formula Containing Probiotics
  Author(s): Anna Nowak-Węgrzyn, Laura A Czerkies, Heidi M Storm, Rosa Real, Barbara Collins and José M SaavedraAnna Nowak-Węgrzyn, Laura A Czerkies, Heidi M Storm, Rosa Real, Barbara Collins and José M Saavedra
  
  Objective: The American Academy of Pediatrics (AAP) defined an infant formula as hypoallergenic if it ensures with 95% confidence that 90% of infants/children with confirmed cow’s milk protein allergy (CMA) do not react under double-blind, placebo-controlled conditions. The aim of this study was to determine whether a new 100% whey protein extensively hydrolyzed formula containing B. lactis CNCM I-3446, meets AAP hypoallergenicity criteria. Methods: Children with CMPA were randomized to double-blind placebo-controlled food challenges (DBPCFC) with a new extensively hydrolyzed formula (Test) and a commercial extensively hydrolyzed formula (Control) in a cross-over fashion. CMPA was confirmed by elevated serum cow’s milk (CM)-IgE levels, positive skin prick test to CM extract, or positive CM oral challenge within 6 months pr.. View More»
  DOI: 10.4172/2155-6121.1000221

  Abstract PDF