Journal of Pharmacovigilance

Annabelle A Ribo

Publications

• Case Report
  Ertapenem-induced Neuropsychiatric Symptoms in an Elderly Patient with Chronic Kidney Disease Resulting to a Prescribing Cascade
  Author(s): Ferdinand Z Ribo and Annabelle A Ribo Ferdinand Z Ribo and Annabelle A Ribo
  
  Seizure as a rare but a major side-effect of carbapenems are widely reported in literature but non-seizure, neuropsychiatric events have scarce, limited information available. Objectives: To present a case report of an elderly patient with chronic kidney disease who had neuropsychiatric effects during ertapenem therapy leading to additional prescribing of anti-psychotic/sedating medications to manage adverse drug events. We present a case of an 85 year old female patient without prior CNS disorder who developed visual hallucinations, agitation, disorientation, sleeplessness after 3 days of ertapenem 1 g therapy. The patient was prescribed with quetiapine and valproic acid to initially manage restlessness and donepezil was later added. Ertapenem was discontinued after day 7 of therapy while agents to manage agitation were continued... View More»
  DOI: 10.4172/2329-6887.1000152

  Abstract PDF