Journal of Blood Disorders & Transfusion

Amira Nashaat Abd El-Gawad

Publications

• Research Article
  Association of Activated Circulating Endothelial Cells with Vascular Complications in Egyptian Beta-Thalassemic Patients
  Author(s): Afaf Abd Elaziz Abd Elghaffar, Soha Raouf Youssef, Deena Mohamed Mohamed Habashy, Mona Ali Mohamed Hassan, Nevine Nabil Mostafa, Gihan Mohamed Kamal and Amira Nashaat Abd El-GawadAfaf Abd Elaziz Abd Elghaffar, Soha Raouf Youssef, Deena Mohamed Mohamed Habashy, Mona Ali Mohamed Hassan, Nevine Nabil Mostafa, Gihan Mohamed Kamal and Amira Nashaat Abd El-Gawad
  
  Background: There is evidence of an association between circulating endothelial cells (CECs) and vascular complications in thalassemic patients. Objectives: To quantify CECs and its activated fraction (AECs) in Egyptian ß-thalassemic patients and to investigate their association with incidence of vascular complications. Subjects and Methods: Eighty pediatric patients and 30 healthy pediatric volunteers were studied for the proportion of CECs and AECs using cellular expression of endothelial adhesion receptors: CD146 and CD106 by flow cytometry. Results: CECs, AECs were higher in patients’ group than control group (p=0.001). AECs, serum ferritin, total leucocyte count (TLC), platelet (PLT) count were higher in patients with vascular complications and splenectomized patients (p=0.001fo.. View More»
  DOI: 10.4172/2155-9864.1000273

  Abstract PDF