Clinical & Medical Biochemistry

Allison McClements

Publications

• Research Article
  Longitudinal Changes in Thyroid Hormones During Conception Cycles and Early Pregnancy
  Author(s): Kristina Hamilton, Narelle Hadlow, Peter Roberts, Patricia Sykes, Allison McClements, Jacqui Coombes and Phillip Matson Kristina Hamilton, Narelle Hadlow, Peter Roberts, Patricia Sykes, Allison McClements, Jacqui Coombes and Phillip Matson
  
  Objective: The aim of this study was to characterize changes in free triiodothyronine (fT3), free thyroxine (fT4) and thyroid-stimulating hormone (TSH) during the follicular and luteal phase and during subsequent early pregnancy in individual women. Method: TPOAb negative women with a viable pregnancy (n=49) had fT3, fT4 and TSH measured longitudinally in serum samples at baseline/non-pregnant (gestation week 0), ovulation (gestation week 2), mid-luteal phase (gestation week 3) and twice weekly from gestation weeks 4 to 6.5. Patient groups received in their conception cycle either no medication (n=13), low ovarian stimulation, (n=17) or controlled ovarian hyperstimulation (COH) for IVF treatment (n=19). Results: Women receiving COH had a transient drop in TSH at the time of ovulation followed by a peak at midluteal.. View More»
  DOI: 10.4172/2471-2663.1000125

  Abstract PDF