Cardiovascular Pharmacology: Open Access

Aivars Lejnieks

Publications

• Research Article
  Methods for Detection of Direct Oral Anticoagulants and their Role in Clinical Practice
  Author(s): Katrina Pukite, Ketija Apsite, Irina Pupkevica, Ilze Cernevska, Oksana Boichuk, Janis Meisters, Dagnija Straupmane, Inga Urtane, Aivars Lejnieks and Oskars KalejsKatrina Pukite, Ketija Apsite, Irina Pupkevica, Ilze Cernevska, Oksana Boichuk, Janis Meisters, Dagnija Straupmane, Inga Urtane, Aivars Lejnieks and Oskars Kalejs
  
  Introduction: Atrial fibrillation (AF) is the most common arrhythmia that increases by age, doubles for every decade after age of 50 years and reaches about 10% patients ≥ 80 years. Despite direct oral anticoagulants (DOACs’) predictable pharmacokinetics and pharmacodynamics, the laboratory tests are necessary for effective and safe medical treatment, also for prediction and detection of thrombotic and bleeding events, as well as in situations when temporary discontinuation could be desirable. Aim: of this study was to identify and analyze the need of coagulation tests for AF patients with high cardiovascular risk in clinical practice. Methods: Quantitative, analytic, cross-sectional clinical trial, during the period from October 2016 till June 2017, was performed at Pauls Stradins Clinical University Hospital, .. View More»
  DOI: 10.4172/2329-6607.1000247

  Abstract PDF