Ahmed Esmael
Department of Microbiology, Immunology and Parasitology, Debre Markos University,
Ethiopia
Research Article
Drug Resistance Pattern of Mycobacterium tuberculosis in Eastern
Amhara Regional State, Ethiopia
Author(s): Ahmed Esmael, Ibrahim Ali, Mulualem Agonafir, Mengistu Endris, Muluworke Getahun, Zelalem Yaregal and Kassu Desta
Ahmed Esmael, Ibrahim Ali, Mulualem Agonafir, Mengistu Endris, Muluworke Getahun, Zelalem Yaregal and Kassu Desta
Background: Tuberculosis (TB) is a major public health problem in Amhara region, Ethiopia where the TB case detection rate is low (22%). This situation has been worsened by the emergence and spread of drug resistance strains which have been threatening efforts of TB control. Objectives: The aim of this study was to assess the magnitude of drug resistance patterns of M. tuberculosis in Eastern Amhara region, Ethiopia. Methods: A facility based cross sectional study was conducted among 230 (165 new and 65 retreated) smear positive TB patients (age ≥18 years old) from September 2010 to June 2011. Socio-demographic data of the study participants and possible factors for development of drug resistance were collected using pre-tested structured questionnaire. Smear positive sputum samples were processed and decontaminated by the modified Petrof method. Primary isolation and drug suscepti.. View More»
DOI:
10.4172/1948-5948.1000125