Agustin Correa
Uruguay
Research Article
In Search of Topical Agricultural Biofungicides: Properties of the
Recombinant Antimicrobial Peptide Trxaq-AMP Obtained from
Amaranthus quitensis
Author(s): Diego Alem, Paola Díaz-Dellavalle, Carolina Leoni, Salvatore G De-Simone, Agustin Correa, Pablo Oppezzo and Marco Dalla RizzaDiego Alem, Paola Díaz-Dellavalle, Carolina Leoni, Salvatore G De-Simone, Agustin Correa, Pablo Oppezzo and Marco Dalla Rizza
Synthetic pesticides have a positive impact on food production. However, there are concerns due to the outbreak of resistance along with negative side effects on human health and the environment. New active compounds and control strategies are needed for the management of phytopathogens. Antimicrobial peptides (AMPs) are evolutionarily conserved components of the innate immune response in almost all organisms that constitute an interesting source of potential molecules for use as pesticides. The naturally derived antimicrobial peptide Aq-AMP (Amaranthus quitensis-Antimicrobial Peptide), obtained from Amaranthus quitensis, is cysteine-rich with activity against several phytopathogens. In the present work, we report on the expression in Escherichia coli of functionally active Aq-AMP fused to thioredoxin (TrxAq-AMP). The in vitro antifungal activity of purified TrxAq-AMP was confirmed ag.. View More»
DOI:
10.4172/1948-5948.1000155