Journal of Stem Cell Research & Therapy

Abeer M. El-Mahalaway

Publications

• Research Article
  Effect of Methyl Mercury on the Cerebellar Cortex of Rats and the Possible Neuroprotective Role of Mesenchymal Stem Cells Conditioned Medium. Histological and Immunohistochemical Study
  Author(s): Nahla El-Eraky El-Azab, Abeer M. El-Mahalaway and Dina SabryNahla El-Eraky El-Azab, Abeer M. El-Mahalaway and Dina Sabry
  
  BACKGROUND: Methyl mercury (Me Hg) is an environmental toxin associated with many serious neurological disorders. Conditioned Medium (CM) derived from Mesenchymal Stem Cells (MSCs) is a novel promising approach for the treatment of nervous system damage and various diseases. OBJECTIVE: The aim of this research is to assess the consequence of Me Hg on the rats’ cerebellar cortex and the potential neuroprotective effect of MSCs – CM. MATERIALS AND METHODS: Forty adult male albino rats were divided into four groups: Group I: control rats; Group II: Me Hg chloride treated rats; Group III: Me Hg chloride and DMEM treated rats; Group IV: CM treated rats after injection with Me Hg chloride. Cerebellar specimens were taken and handled for histological and immunohistochemical techniques. Morphometrical studies and statistical analysis were performed. RESULTS: Groups II and III show.. View More»
  DOI: 10.4172/2572-4126.1000430

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