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Aarón Rebollar
Aarón Rebollar
Spain
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Research Article
A Novel Cecropin A-derived Peptide as Specific Inhibitor of Appressoria in Magnaporthe oryzae
Author(s): Aarón Rebollar and Belén López- GarcíaAarón Rebollar and Belén López- García
Magnaporthe oryzae causes crop losses around the world and is considered one of the most harmful pathogens in rice. The search for new types of antifungal compounds focuses on specificity in order to avoid toxicity to non-target species. In this work, we characterized the activity of the natural antimicrobial peptide Cecropin A and its derived peptide MgAPI16 as inhibitors of appressorium formation in M. oryzae. These peptides were able to control the development of blast disease in rice plants. Several lines of evidence indicated the different mode of action of both peptides. The addition of inducers of appressorium formation interfered with the inhibitory effect of MgAPI16 but not with Cecropin A. Moreover, antimicrobial activity assays showed a weak or no toxicity of MgAPI16 against bacteria and fungi suggesting high specificity in inhibiting appre.. View More»
DOI: 10.4172/2157-7471.1000336