Oral Health and Dental Management

Abstract

Well-differentiated Squamous Cell Carcinoma and a Foreign Body Reaction – A Case Report

Martins Allisson FL, Arantes Diego AC, Bellotti Alexandre, Mendonça Elismauro F

Squamous cell carcinoma (SCC) is a common malignancy that can affect the oral cavity. This neoplastic lesion is characterized by the presence of malignant squamous epithelial cell nests, keratin pearls, individual cell dyskeratosis, and atypical cells surrounded by a chronic inflammatory infiltrate. An uncommon event in this inflammatory infiltrate is the presence of multinucleated giant cells (MGCs) in the SCC stroma, and hence the clinical relevance and the true nature of SCC presenting this type of cells need to be clarified. We report a case of a well-differentiated oral cavity SCC presenting MGCs that was analyzed by immunohistochemistry to establish the origin of these cells.