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Abstract
Underlying Mechanism of Coffee as Inhibitor Adipogenesis for Complementary Medicine Use in Obesity
Introduction: Obesity is a problem that affects the world community for early mortality. Coffee is the favorite drink that contains caffeine and the main form has been consumed since the days of our ancestors. Caffeine was considered to have a negative effect on health, but the most current studies prove that caffeine is beneficial to health, as well as in the treatment of obesity, but not much is understood about the mechanism of action of caffeine for obesity. The purpose of this paper to discuss the mechanism of weight loss in the form of coffee contains caffeine. Methode: Systematic review. Result: Caffeine of coffee has properties as an inhibitor of adipogenesis. Discussion: Caffeine has thermogenesis effect which can reduce the size and number of adipose cells so that the accumulation of adipose tissue will be reduced. Finally, the weight will come down and achieved improvement of organ function and adipose tissue. Conclusion: Caffeine coffee potentially loses weight obese due to their properties as an inhibitor of adipogenesis of caffeine of coffee.