Journal of Vascular Medicine & Surgery

Abstract

Second Generation DES: Better Option in Treatment ISR

Nadezhda Hristova, Trendafilova D and Jorgova J

The development of an effective strategy for treatment of in-stent restenosis after BMS placement has been found to be extremely complicated. The therapeutic purpose for many patients is achieved with the implantation of DES – an option which is still not investigated and studied enough. 152 patients with implanted drug-eluting stents (different generations) for severe in-stent restenosis were followed up for a period of 9 years in the department of cardiology of University Hospital “St. Ekaterina”. Patients were divided into two groups – 131 patients with implanted first generation DES, and 21 patients – with second generation DES. Patients were followed up clinically (reversed angina, MI, emergency CABG, death), EchoCG and/or ECG stress test. Patients with angina pectoris and/or decreased LV function were assessed by conventional or CT angiography. Serious complications were not observed. 9 patients were with significant in-stent proliferation, and the others were with patent stents. Implementation of DES for treatment of in-stent restenosis is an established method, because of its reliability and safety with low percentage of complications.