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Abstract
Research Progress Using Zebrafish as A Model Animal to Monitor Pollution in Bohai Bay
Liu Chunyu, Dong Wenjing, Xue Jiangdong*, Dong Wu
Zebrafish have many advantages as model animals, such as small size, easy operation, sensitivity to chemicals, and abundant transgenic models. Recent studies have used zebrafish as a model animal to select available biomarkers for monitoring pollution in the surrounding areas of Bohai Bay, and the studies have made significant research progress. Notable, CYP1A expression and eye pigmentation serve as biological indicators, which can be used to quickly and widely monitor the environmental quality and ecological health status around Bohai Bay. This review summarizes the research progress on the use of zebrafish as a model animal for monitoring pollution in Bohai Bay. The study verified that the use of CYP1A transgenic zebrafish is a rapid, sensitive, cost-effective method that can be used to monitor harmful substances in the environment.
Published Date: 2025-06-12; Received Date: 2024-01-17