Non Valvular Atrial Fibrillation Related Ischaemic Stroke at the Teaching Hospital of Yalgado Ouedraogo, Burkina Faso

Mandi D Germain, Samadoulougou K André, Yaméogo R Aristide, Millogo RC Georges, Naïbé D Temoua, Kaboré PK Hervé, Kologo K Jonas and Zabsonré Patrice

Objectives: We aim to describe the epidemiological and prognostic characteristics of non valvular atrial fibrillation related stroke.
Patients and methods: We retrospectively analyzed data of hospitalized patients from January 1st 2010 to June 30th 2012 in the two contiguous departments of cardiology and neurology, at the teaching hospital of Yalgado Ouédraogo, Burkina Faso.
Results: We recorded 391 cases of ischaemic stroke. Cardioembolic stroke was observed in 159 patients out of who, non valvular atrial fibrillation accounted for 43.5%. Atrial fibrillation was persistent/permanent in 60 cases (87%). The mean age ± SD was 63.3 ± 14.2 years (extremes: 26-91 years). Hypertension was observed in 85.5% of the cases. The mean CHA2 DS2 -VASc score was 4.72 ± 1.16. The mean HAS-BLED score was 2.35 ± 0.92 with a low to intermediate bleeding risk score (≤ 2) in 60.9 % of patients. The rate of vitamin K antagonists use was 52%. They were introduced at least a week after stroke onset in 34 cases. A mean follow up of two weeks in hospital noticed haemorrhagic transformation and ischaemic recurrence in respectively 8.7% and 2.9% of the cases. Mortality rate of 21.7% during hospitalization was predicted by large sized cerebral infarction and congestive heart failure (p<0.05).
Conclusion: Non valvular atrial fibrillation stroke is associated with in-hospital high mortality and is subject to early recurrence.