Abstract

Green Synthesis of Chromium(III) Oxide Nanoparticles and their Evaluation against Skin Infections

Nadia Bukhari, Muhammad Waris, Muhammad Iqbal Khan, Naila Gul and Farhana Anjum*

Nanotechnology is an important area of contemporary research since it addresses the size, structure, and composition of the products to be produced. Chromium(III) Oxide (Cr2O3) nanoparticles were prepared using fixed ratio of plant extract (Psidium guajava) which contain reducing sugars as reducing agent and Potassium Dichromate (K2Cr2O7) solution. The applications of Cr2O3 nanoparticles against different human pathogens were investigated. The synthesized nanoparticles were characterized with different characterization techniques which were UV-Vis, XRD, SEM and FTIR. UV-Vis analysis was used to confirm the initial spectra of Cr2O3 nanoparticles. Broad absorbance was observed in the range of 310 to 500 nm and high absorbance at 370 nm confirmed the synthesis of Cr2O3 nanoparticles. The nanoparticles were found to have the size of 33 nm according to XRD. All the desired peaks of plant and metal oxide were also present in FT-IR spectra. SEM showed particles were irregular in shape and poly dispersed. To know about the antifungal activities the plates were incubated at 28°C for 48 h, and after this period fungal growth inhibition zone were measured. It was found that Cr2O3 nanoparticles have shown good antifungal activities against different skin infection pathogens.

Published Date: 2025-10-21; Received Date: 2024-11-07