Journal of Carcinogenesis & Mutagenesis

Abstract

Early Onset Cancer of the Cervix Incidence Increasing in Young HIV Negative Women in Western Kenya-A Case Study of Jaramogi Oginga Odinga Teaching and Referral Hospital

George Ogutu, Arthur Ajwang*, Khama Rogo, Shem Sam Otoi, Jogchum Beltman and Benson Estambale

Background: In many Low and Middle Income Countries (LMIC) HIV and cervical cancer have always been interlinked, as HIV patients are more likely to develop Early Onset cervical cancer, hence the researched and published studies of young age at diagnosis of the women with HIV. At the Jaramogi Hospital (JOOTRH) Kenya we have lately been recording an increase of incidences of Early Onset cancer of the cervix in HIV negative women, mean age of 23.

Objective: This study aimed at examining the incidence of Early Onset Cervical Cancer in HIV negative women, presenting at the Oncology Clinic.

Methodology: A mixed method study was undertaken, with a review of hospital records of all patients aged 13-35 years presenting with Cancer of the Cervix regardless of HIV status at time of diagnosis from 2012-2019 period of the study and purposive active recruitment of<35 done in the period of 2020-2021.

Results: There is a significant increase in Early Onset Cancer of the Cervix in the Prospective arm (2020-2021) with P-value 0.017 at CI (2.562, 18.938) as compared to the Retrospective arm (2012-2019) with P-value 0.012 at CI (1.921, 11.079).

Conclusion: We concluded that Early Onset Cancer of the Cervix Incidence in HIV Negative women is increasing substantially in Western Kenya.

Published Date: 2023-12-11; Received Date: 2023-11-10