Cystic fibrosis (CF) is an inherited disorder that causes severe damage mostly to the lungs but also the digestive system including pancreas, liver, kidneys and intestine. In this disease the secretory fluids mucus, sweat and digestive juices become thick and sticky. Instead of acting as a lubricant, the secretions plug up tubes, ducts and passageways, especially in the lungs and pancreas. CF is most common in white people of Northern European ancestry, but also occurs in Hispanics, African-Americans and some Native Americans and rare in Asian. The disease occurs in 1 in 2,500 to 3,500 white newborns and affecting 70,000 people worldwide.