Fifth disease is a viral infection caused by parvovirus B19. The virus only infects humans; it's not the same parvovirus that dogs and cats can get. Fifth disease mostly affects children. Symptoms can include a low fever, cold symptoms, and a headache. Then you get a red rash on your face. It looks like a "slapped cheek." The rash can spread to the arms, legs, and trunk. Adults who get it might also have joint pain and swelling.
Fifth disease is caused by a virus that often results in a red rash on the arms, legs, and cheeks. For this reason, it is also known as “slapped cheek disease.” It is fairly common and mild in most children, but it can be more severe for pregnant women or anyone with a compromised immune system.