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Short Communication - (2020) Volume 12, Issue 5

Short Communication on Recent Published Articles in Journal of Microbial & Biochemical Technology
Mamatha Dereddy*
 
Sri Indu Institute of Pharmacy, Hyderabad, India
 
*Correspondence: Mamatha Dereddy, Sri Indu Institute of Pharmacy, Hyderabad, India, Email:

Received: 25-Aug-2020 Published: 25-Aug-2020, DOI: 10.35248/1948-5948.20.12.440

Abstract

Very recently severe acute respiratory syndrome CoV 2 (SARS-CoV-2) that caused coronavirus disease 2019 (COVID-19) has been detected in the neural and capillary endothelial cells of the frontal lobe in postmortem tissue of a patient. Besides, the association of neurological symptoms such as confusion, impaired consciousness, headache, meningitis, acute stroke, encephalitis, hemorrhage, seizure and early symptoms of Guillian-Barre like symptoms in the SARS-CoV-2 patients has raised great concern about the potential impact of the neuroinvasion of SARS-CoV-2. However, the exact pathomechanism of the SARS-CoV-2 infection is not completely understood. Lack of study on the SARS-CoV-2 mediated infection of the central nervous system (CNS) makes it difficult to evaluate how SARS-CoV-2 invades the nervous system and causes neuronal damage and cognitive impairment. Here, we discuss the neurological manifestations of COVID 19, the pathomechanism, and possible route of invasion of SARS-CoV-2 in the CNS. We also emphasize the importance of better understandings of neuroinvasion of SARS-CoV-2 to develop better therapeutic approaches to treat COVID 19 related neurological complications.

Keywords

Microbial & Biochemical Technology; E.coli; human immunodeficiency virus; Glucoamylase; Alzheimer's disease

Introduction

Expression and Applications of HriCFP in E. coli: A Novel Biosensing Fluorescent Protein in this article the author Habib Bokhari clearly explained the biosensing potential of a novel fluorescent protein called HriCFP. The protein was expressed in the E.Coli which presented stable and discreet expression in the bacterial cells. It also shows that HriCFP may have substantial advantage over other larger proteins because of its minimal impact on host strain metabolism.

Diagnostic oral biomarkers of immunosuppression in apparently healthy seropositive HIV population, in South Western Uganda in this article the author Agwu Ezera clearly presented the evaluation of the oral clinical manifestations as biomarkers of immunosuppression in the healthy people of human immunodeficiency virus infected patients in resource poor masaka, mbarara and rakungiri districts of south western Uganda.

Solid-State Fermentation of Agroindustrial Residues for Glucoamylase Production from Endophytic Fungi Penicillium javanicum of Solanum tuberosum L. in the article the author Mervat Morsy Abbas Ahmed El-Gendy has clearly evaluated the glucoamylase production under the solid state fermentation of residues of agro industries along with groundnut shell, corn stover, wheat straw etc as renewable cheap substrates from the roots of solanum tuberosum L. The result presented the yield of maximum glucoamylase using groundnut shell as substrate.

Theoretical Study of Quinoline Derivatives Involved in Neurodegenerative Diseases in the paper the author Soufi Wassila explained in detail about the neurogenitive diseases in detail and found that a series of quinoline derivative has been synthesized with a very high heterocyclic class in a wide range of biological activities. These derivatives have been revealed to be selective inhibitors of Acetyl cholinesterase (AChE) with IC50 values. This work is to study the inhibition of AChE enzyme involved in the Alzheimer's disease by computational methods for molecular modeling and simulation of macromolecule. These results will probably help in the development of an effective therapeutic tool to fight against the development of Alzheimer's disease.

Reduce the Risk of Oxidation and Pathogenic Bacteria Activity by Moringa oleifera Different Leaf Extract Grown in Sudan in this the author the Rasha Khalid Abbas clearly presented to identify the Polyphenol constituents of Moringa oleifera leaf extract by different methods using High Performance Liquid Chromatography. Ellagic acid gave the highest concentration when extracted by ethyl acetate Caffeine gave the lowest concentration. in all different extract, The effect of leaf extracts against four different pathogenic bacteria Salmonella typhimurium, Pseudomonas aeruginosa, Escherichia coli, and Bacillus cereus, were inspected using Mueller Hinton Agar and calculating inhibition zone (diameter mm), were found that, there was significant difference of all moringa leaf extracts against bacteria.

Citation: Mamatha Dereddy (2020) Short Communication on Recent Published Articles in Journal of Microbial & Biochemical Technology. J Microb Biochem Technol 12:440. doi: 10.35248/1948-5948.20.12.440

Copyright: © 2020 Dereddy M. This is anopen access article distributed under the term ofthe Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction inany medium, provided theoriginal work isproperly cited.

Competing interests: The authors have declared that no competing interests exist.