Journal of Microbial & Biochemical Technology

Microbial Biosensors: A Review

Jessica Moore^{*# 1}Microbiology, University of Washington, United States
^#Equally contribution ^*Correspondence: Jessica Moore, Microbiology, University of Washington, United States, Email:

Received: 02-Jun-2021 Published: 25-Jun-2021, DOI: 10.35248/1948-5948.21.13.475

Introduction

Biosensors are analytical instruments used to detect or distinguish particular components. Since Clark created the first biosensor in 1962 (1), biosensors have been widely investigated and extensively utilised in a variety of circumstances due to their tremendous potential. Biosensors are often classified according to their core platforms, which include antibodies, protein receptors (2), enzymes (3), and microorganisms. Because of their great specificity and sensitivity, enzymes and nucleic acid oligonucleotides have been used in the majority of biosensors in practical and clinical usage in recent decades (4).

Many improved microbial biosensors have been described in recent decades, showing promise for a wide range of applications. Microbial biosensors are analytical devices that are made up of a microbe that detects a target substrate and transforms the observed signal to a measurable response in a physiological, electrical, or biochemical manner.

As previously said, microorganisms such as bacteria and yeast provide a viable method for building microbial biosensors with several advantages. First, biosensors based on microorganisms have a significantly cheaper analytical cost for sensing components than other approaches using traditional instruments such as gas chromatography, liquid chromatography, mass spectrophotometry, and others (5).

Conclusion

The combination of micro/nanotechnologies with microbial biosensors, as well as their applications. Microbial biosensors have been the subject of extensive research in recent decades, but they appear to be restricted by a number of issues, including low sensitivity, poor selectivity, complex sensor architecture, and stochastic heterogeneity. To address such constraints, microbial biosensors have been combined with several modern micro/nanotechnologies as multidisciplinary convergence research has grown rapidly.

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