Influenza Virus-like Particles Containing HA, NA, and M1 Induced Protection in Chickens against a Lethal Challenge with the Highly Pathogenic H5N1 Avian Influenza Virus

Motofumi Shimizu¹, Satomi Yanase¹, Chang Myint OO², Masatoshi Okamatsu³, Yoshihiro Sakoda³, Hiroshi Kida³ and Hiroshi Takaku^1,2*

¹Department of Life and Environmental Sciences, Chiba Institute of Technology, 2-17-1 Tsudanuam, Narashino, Chiba 275-0016, Japan

²High Technology Research Center, Chiba Institute of Technology, 2-17-1 Tsudanuam, Narashino, Chiba 275-0016, Japan

³Laboratory of Microbiology, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan

^*Corresponding Author: