Genetically Engineered Mesenchymal Stem Cells Influence Gene Expression in Donor Cardiomyocytes and the Recipient Heart

Mary Kearns-Jonker^1,3,4*, Wangde Dai^2,3, Mirja Gunthart¹, Tania Fuentes⁴, Hsiao-Yun Yeh⁴, Paul Gerczuk², Martin Pera³, Christine Mummery⁵ and Robert A Kloner^2,3

¹Dept of Cardiothoracic Surgery, Childrens Hospital Los Angeles, Los Angeles, CA, USA

²Heart Institute of Good Samaritan Hospital, Los Angeles, CA, USA

³Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern CA Keck School of Medicine, Los Angeles, CA, USA

⁴Dept of Pathology and Human Anatomy, Loma Linda University School of Medicine, Loma Linda, CA, USA

⁵Dept of Anatomy and Embryology, Leiden University Medical Center, Leiden, Netherlands