Acquisition of Cancer Stem Cell Behaviour Plays a Role in Drug Resistance to Combination Chemotherapy and Prognosis in Head and Neck Cancer

Research Article - (2015) Volume 5, Issue 1

Sindhu Govindan Valiyaveedan^1,⁷, Balaji Ramachandran², Jeyaram Iliaraja³, Ravindra DR¹, Bonney Lee James¹, Kulsum Safeena¹, Ramanan Pandian⁴, Gangotri Siddappa^1,⁷, Debashish Das⁵, Nisheena R⁶, Aravindakshan Jayaprakash², Vikram Kekatpure⁷, Wesley Hicks Jr^8,⁹, Moni A Kuriakose^1,^7,⁹ and Amritha Suresh^1,^7,⁹^*: ¹DSRG-5, Mazumdar Shaw Centre for Translational Research, Mazumdar Shaw Medical Foundation, Bangalore, India; ²Department of Pharmacology, Syngene International Pvt Ltd, Biocon, Bangalore, India; ³Department of Clinical Research, Mazumdar Shaw Medical Center, Narayana Health, Bangalore, India; ⁴GROW Laboratory, Narayana Nethralaya, Narayana Health City, Bangalore, India; ⁵Stem Cell Research Laboratory, Narayana Nethralaya, Narayana Health City, Bangalore, India; ⁶Department of Pathology, Mazumdar Shaw Medical Center, Narayana Health, Bangalore, India; ⁷Department of Head and Neck Oncology, Mazumdar Shaw Medical Center, Narayana Health, Bangalore, India; ⁸Department of Head and Neck/Plastic & Reconstructive Surgery, Roswell Park Cancer Institute, Elm Street, Buffalo, USA; ⁹Mazumdar Shaw Medical Centre-Roswell Park Collaboration Program, Roswell Park Cancer Institute, Elm Street, Buffalo, USA

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