Research Article - (2015) Volume 4, Issue 1

A Novel ASK Inhibitor AGI-1067 Inhibits TLR-4-Mediated Activation of ASK1 by Preventing Dissociation of Thioredoxin from ASK1

Li Y1, Zheng S2, Long L2, Jenny Zhou H2,3, Ji W2 and Min W2,3*
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
2The Center for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
3Interdepartmental Program in Vascular Biology and Therapeutics, Dept. of Pathology, Yale University School of Medicine, New Haven, CT, USA
*Corresponding Author: