20+ Million Readerbase
Indexed In
  • Open J Gate
  • Genamics JournalSeek
  • Academic Keys
  • RefSeek
  • Hamdard University
  • EBSCO A-Z
  • OCLC- WorldCat
  • Publons
  • Geneva Foundation for Medical Education and Research
  • Google Scholar
Share This Page
Recommended Webinars & Conferences
Journal Flyer
Flyer image

Abstract

The Efficacy of L-Carnitine for Fanconis Syndrome caused by Long-Term Administration of Adefovir Dipivoxil(Adv) in a Patient with Chronic Hepatitis B: A Case Report

Hiroto Tanaka, Hideyuki Sasaki and Mikio Arita

A 51-year-old female with chronic hepatitis B treated by Lamivudine (LAM) and Adefovir Dipivoxil (ADV) because of breakthrough hepatitis developed hypophosphatemia. She was diagnosed with Fanconi’s syndrome caused by the long-term administration of ADV. Since her symptoms did not improve after decreasing the ADV dosage and administering vitamin D, she was given L-carnitine. This led to a gradual improvement of her symptoms and the hypophosphatemia. These results indicate that a decrease in the ADV dose combined with supplementation with L-carnitine led to an improvement of Fanconi’s syndrome acquired by a patient with chronic hepatitis B while taking ADV.