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Screening and Isolation of Antagonistic Actinobacteria Associated With Marine Sponges from Indian Coast

Sunanda Kumari Kadiri, Nagendra Sastry Yarla and Siddaiah Vidavalur

Sponges are host organisms for various symbiotic microorganisms such as Archea, Bacteria, Cyanobacteria and Microalgae. Sponges associated microorganisms are sources of wide variety of useful natural products like antibiotics, anti-inflammatory, antioxidant, antiviral, antifouling and cytotoxic compounds. Nearly 60 isolates of action bacteria were found to be associated with 6 species of marine sponges collected at various locations. The isolates were screened for antimicrobial activity against 6 pathogenic bacteria and 4 pathogenic fungi. Among 60 isolates, 15 isolates showed antibacterial activity and 6 isolates showed antifungal activity. Among active isolates, isolate no.42 showed highest antimicrobial activity against all the pathogenic bacteria and fungi studied and it was identified as streptomyces species.