New Generation Combination Vaccines against Streptococcus pyogenes

Rasmus Mortensen and Jes Dietrich

With our recent discovery of new protective non-M protein antigens expressed by Streptococcus pyogenes, as well as the characterization of GAS cellular and humoral immunity in human adults and children, we encourage the development of new combinational GAS vaccines, with the ability to induce Th1/Th17/IgG3 based memory immunity in humans.