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Abstract

Microbial Interactions with Nanostructures and their Importance for the Development of Electrospun Nanofibrous Materials used in Regenerative Medicine and Filtration

Chris J Mortimer, Luke Burke and Chris J Wright

The growing use of electrospinning to fabricate nanofibrous structures for use in wound dressings, tissue engineering, and filtration processes has increased the need for an understanding of the interactions between bacteria and nanostructures. The adhesion characteristics and colonization of bacteria on these materials is still not completely understood but is essential to aid their future development. This review presents the state of current research on microbial attachment at materials with micro- and nanostructures and how this research has been developed and adapted to study the interactions of bacteria with nanofibres. The few studies to date are discussed with the view to identifying the future studies required to increase understanding and allow the technology and application of electrospun nanofibres to move forward.