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Invasive Fungal Infection by Hormographyella aspergillata: A Tricky Diagnosis Triggered by (1,3)-Beta-D-Glucan Assay

Raffaella Koncan, Gianpaolo Nadali, Vincenza Favuzzi, Marco Ligozzi, Annarita Sorrentino and Giuliana Lo Cascio

We report on a pulmonary infection caused by the basidiomycete Hormographiella aspergillata. For the first time, (1,3)-beta-D-Glucan serum levels were monitored and they progressively increased during the development of clinical symptoms of infection. This assay and subsequent molecular analysis resulted essential for accurate identification and indication of proper antifungal therapy.