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Factor XI Deficiency in West Algeria: A Case Report and Literature Review

Arabi A, Chekkal M, Cheref L, Bouchama S, Mehded S, Brahimi M, Yafour N and Bekadja MA

Factor XI deficiencies are rare. Initially, they were described only in Ashkenazy Jews with two types of characteristic gene mutation. Now, 152 mutations have been identified, mostly in non-Jewish population.
We report the case of a deficiency identified in Arabic young girl living in West Algeria; gene sequences showed a type II mutation, frequent in Ashkenazy Jews. May be it is coincidence; but it is possible that this finding is related to the migratory story of this region.