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Factor XI Deficiency: First Case Described in Algeria

Abdessamed Arabi, Mohamed Chekkal, Leila Charef, Samira Bouchama, Sihem Mehded, Mohamed Brahimi, Nabil Yafour and Mohamed-Amine Bekadja

Factor XI deficiencies are very rare and the first case was registered among Ashkenazy Jews with two types of characteristic gene mutation. Today 152 mutations have been identified even among non-Jewish population. The present study reports the deficiency identified in a young Arabic girl living in West Algeria; gene seqensage with type II mutation was noticed in Ashkenazy Jews frequently. The present study concludes that it is happening either coincidentally or due to the constant migration history of this region.