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Efficacy of Electron Beam for Viral Inactivation

Raymond W Nims and Mark Plavsic

The utility of electron beam as a physical approach for viral inactivation has been investigated to a limited extent, particularly for food safety and for applications for which other irradiation approaches such as gamma irradiation have produced unsatisfactory results or adverse impacts on the irradiated material. Viral inactivation by electron beam and gamma irradiation is mechanistically similar, though dose rate and penetrability into the irradiated material differ between the two approaches. In this paper, we have summarized the available data on the efficacy of electron beam for viral inactivation and the few studies that have directly compared the efficacy of electron beam and gamma irradiation for viral inactivation.