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Comorbidity of Primary Torsion Dystonia with Psychiatric Disorders

Hranov G and Semerdjieva N

The authors investigate and describe comorbidity of PTD with psychiatric diseases reviewing the medical records of all hospitalized patients, diagnosed with PTD for a period of four years. 75 patients with confirmed diagnose of PTD gave their informed consent and were clinically investigated including an examination by a specialist psychiatrist. The majority of the patients with the psychiatric comorbidity experience depressive symptoms, but more importantly a high percent of the patients (4%) suffer from schizophrenia. Therefore one can assume that there is an abnormality in the common cerebellar pathways in the brain in PTD and schizophrenia.